Disclaimer to the Online Edition
This Manual has been designed for use in the NICU at London Health Sciences Centre (LHSC), London, Ontario, Canada, and represents clinical practice at this institution. The information contained within the Manual may not be applicable to other centres. If users of this Manual are not familiar with a drug, it is recommended that the official monograph be consulted before it is prescribed and administered. Any user of this information is advised that the contributors, Editor and LHSC are not responsible for any errors or omissions, and / or any consequences arising from the use of the information in this Manual.
aldactazide® (spironolactone-hydrochlorothiazide)
Indication
- Diuretic used to treat mild to moderate edema and hypertension or chronic lung disease with pulmonary edema
Dosage Guidelines
- 1-2 mg of each component/kg/dose q12 hours
Administration
- Oral
Adverse Effects
- Hyponatremia, hypo/hyperkalemia, hypocalcemia, hypomagnesemia, alkalosis, impaired glucose tolerance, hyperuricemia, vomiting, rash and diarrhea
Comments
- Monitor serum potassium, sodium, weight change, fluid status and blood pressure
- Caution in patients with renal or hepatic failure
Supplied As
- 5 mg/mL oral suspension (each mL contains 5 mg each of hydrochlorothiazide and spironolactone) prepared by Pharmacy.
References
LexiComp Sick Kids, LexiComp Pediatric and Neonatal