atropine
Indication
- An anticholinergic agent used to treat sinus bradycardia caused by excessive vagal stimulation
- To inhibit salivation and reduce excessive secretion within the respiratory tract
- To prevent reflex bradycardia from vagal stimulation during intubation
Dosage Guidelines
For bradycardia:
- 0.01-0.03 mg/kg (10 to 30 mcg/kg)/dose IV/IM/SUBCUT/ETT
- May repeat every 10-15 minutes, maximum total dose of 0.04 mg/kg (40 mcg/kg)
For elective intubation:
- 0.02 mg/kg (20 mcg/kg) IV
Administration
- IV direct over 30 seconds to 1 minute by MD/NP or under direct supervision by MD/NP
- IM
- SUBCUTANEOUS
- ETT by MD/NP or under direct supervision by MD/NP
Adverse Effects
- Tachycardia, dilated pupils, dry mucous membranes, flushed skin with rash, and abdominal distention with absent bowel activity
Comments
- Consult the Neonatal Premedication for Endotracheal Intubation Standardized Dosing Chart for weight-banded dose and volume found on the LHSC NICU Intranet Site
Supplied As
- 0.4 mg/mL (400 mcg/mL), ampoule
References
Lexi Sick Kids, Lexi Peds, Neofax