budesonide
Indication
- An inhaled corticosteroid used in the treatment of chronic lung disease
- Prevention of bronchopulmonary dysplasia (BPD) in patients on non-invasive respiratory support
Dosage Guidelines
Treatment of chronic lung disease
- 0.5-1 mg q8-12 hours
- Maximum dose 1 mg q12 hours
Prevention of BPD in patients on non-invasive respiratory support
- 1 mg q12 hours (0800 and 2000) for 21 days followed by 1 mg q24 hours for 7 days
- Assess response to therapy on day 7
Administration
- Via nebulizer over 10-15 minutes
- Dilute to a total of 3 mL with normal saline
- Rinse or swab mouth with sterile water after administration to decrease the risk of oral candidiasis
- Cover eyes during administration and wipe or rinse eyes after administration
- May be mixed with salbutamol and ipratropium solutions just prior to administration
Adverse Effects
- Sore throat, dysphonia, oral candidiasis
Comments
- Monitor mouth/perineum for candidiasis
- Onset: 24 hours
- Maximum effect 3-7 days
Supplied As
- 0.5 mg/mL nebuamp
References
- Lexi Sick Kids, Lexi Peds