cyclopentolate-phenylephrine - CYCLOMYDRIL® (Special Access Medication) *
- Combination product containing cyclopentolate 0.2% and phenylephrine 1%
Indication
- To dilate the pupils of infants for retinal examination
Dosage Guidelines
- 1 drop to each eye; REPEAT in 10 minutes (approximately 60 minutes before eye examination)
Administration
- Ophthalmic
Adverse Effects
- Transient stinging of the eye
- Administration may result in adverse systemic effects (e.g. inhibition of GI tract motility, urinary retention, tachycardia, relaxation of smooth muscle in bronchi and bronchioles, CNS stimulation)
Comments
- Small infants are especially prone to the CNS and cardiopulmonary side effects from systemic absorption of Cyclomydril®
- To minimize systemic absorption, apply pressure over the nasolacrimal sac for 2 to 3 minutes following instillation
- Infants should be watched closely for at least 60 minutes for signs of vasoconstriction (pallor, blanching, mottling), tachycardia, increased blood pressure and apneic spells
- The infant's pupil size should be monitored for 24 hours after instillation of the drops and exposure to bright light should be avoided
- Post a “Protect My Eyes” sign at the bedside for 24 hours post dose
- Feeding progression/tolerance may be affected for 24 hours post dose
- Ophthalmologists will administer topical analgesia prior to eye exam
Supplied As
- CYCLOMYDRIL® ophthalmic solution, 2 mL
- Patient specific bottles expire 30 days after opening
- Pharmacy maintains a future use supply of Cyclomydril® -approval through the Special Access Program is not required prior to initiation
References
Lexi Sick Kids, Lexi Peds