hyaluronidase
Indication
- management of IV extravasations (leakage of an IV fluid out of a vein and into surrounding tissue)
- Not for the management of extravasation due to vasoactive medications (E.G. DOBUTamine, DOPamine, EPINEPHrine, norepinephrine, phenylephrine or vasopressin).
Dosage Guidelines
- Use 2 separate 0.2 mL injections of a 150 units/mL solution into the extravasation site at the leading edge
Administration
- SUBCUTANEOUSLY by MD/NP only
- Use a 25 gauge or smaller needle and change needle after each injection
Adverse Effects
- Injection site reaction
Comments
- NOT the agent of choice for management of extravasation of vasoactive medications
- do NOT inject around infected or inflamed areas
- Most effective if administered within 1 hour of extravasation but still effective up to 12 hours after
Supplied As
- 150 units ampoule (refrigerated)
References
LexiComp Sick Kids, LexiComp Pediatric and Neonatal and Neofax