Disclaimer to the Online Edition
This Manual has been designed for use in the NICU at London Health Sciences Centre (LHSC), London, Ontario, Canada, and represents clinical practice at this institution. The information contained within the Manual may not be applicable to other centres. If users of this Manual are not familiar with a drug, it is recommended that the official monograph be consulted before it is prescribed and administered. Any user of this information is advised that the contributors, Editor and LHSC are not responsible for any errors or omissions, and / or any consequences arising from the use of the information in this Manual.
nystatin
Indication
- Antifungal agent used in the treatment of cutaneous and oral cavity infections caused by Candida
Dosage Guidelines
ORAL: 100,000 – 200,000 units (1-2 mL) q6 hours x 7 to 14 days
Topical: BID to 5 times daily with diaper changes
Administration
- ORAL: give after feeds to each side of the mouth (may be placed onto a cotton swab or into the tip of a nipple to paint the oral cavity). May be swallowed. Avoid feeding for 30 minutes after administration.
- Topical: to buttocks and groin
Adverse Effects
- GI disturbances, rarely hypersensitivity
Comments
- Apply first if other topical medications are being used.
- Symptomatic improvement is seen within 3 days. Continue for 48 to 72 hours after resolution of symptoms.
- If needed for more than 10 days, reassess cause of rash
Supplied As
- 100,000 units/mL oral suspension
- 100,000 units/g topical cream
References
LexiComp Sick Kids, Neofax