nystatin

nystatin

Indication

  • Antifungal agent used in the treatment of cutaneous and oral cavity infections caused by Candida

Dosage Guidelines

ORAL: 100,000 – 200,000 units (1-2 mL) q6 hours x 7 to 14 days

Topical: BID to 5 times daily with diaper changes

Administration

  • ORAL: give after feeds to each side of the mouth (may be placed onto a cotton swab or into the tip of a nipple to paint the oral cavity).  May be swallowed.  Avoid feeding for 30 minutes after administration.
  • Topical:  to buttocks and groin

Adverse Effects

  • GI disturbances, rarely hypersensitivity

Comments

  • Apply first if other topical medications are being used.
  • Symptomatic improvement is seen within 3 days.  Continue for 48 to 72 hours after resolution of symptoms.
  • If needed for more than 10 days, reassess cause of rash

Supplied As

  • 100,000 units/mL oral suspension
  • 100,000 units/g topical cream

References

LexiComp Sick Kids, Neofax