Trauma Research

Trauma Research is a priority for the Program in fulfilling both a regional and provincial role as a Lead Trauma Hospital (LTH). Primary areas of interest in trauma research include injury epidemiology, effectiveness of interventions, and improvement in patient outcomes. Research related to the physiological response to injury (i.e. bench research) is also conducted to a lesser extent.

The Trauma Program has two research teams (adult and paediatric) that are collaborative, interdisciplinary teams responsible for facilitating the development and coordination of trauma research activities at LHSC.

The Trauma Program is also active in multi-centre, collaborative research on a national level through participation in the Canadian Trauma Trials Collaborative, a subcommittee of the Trauma Association of Canada (TAC).

Trauma Research Publications

2018-2024

  1. Jae J, Li Y, Sun C, Allan A, Basmaji J, Chilton S, Simsam MH, Kao R, Owen A, Parry N, Priestap F, Rochwerg B, Smith S, Turgeon AF, Vogt K, Walser E, Iansavitchene A, Ball I. Preclinical Studies on Mechanisms Underlying the Protective Effects of Propranolol in Traumatic Brain Injury: A Systematic Review. J Neuroimmune Pharmacol. 2024 Jun 20;19(1):33. doi: 10.1007/s11481-024-10121-1. PMID: 38900343.
  2. Momic J, Yassin N, Kim MY, Walser E, Smith S, Ball I, Moffat B, Parry N, Vogt K. Antiplatelets versus anticoagulants in the treatment of blunt cerebrovascular injury (BCVI) - A systematic review and meta-analysis. Injury. 2024 Apr;55(4):111485. doi: 10.1016/j.injury.2024.111485. Epub 2024 Feb 27. PMID: 38452701.
  3. Prager R, Walser E, Balta KY, Nikouline A, Leeper WR, Vogt K, Parry N, Arntfield R. Resuscitative transesophageal echocardiography during the acute resuscitation of trauma: A retrospective observational study. J Crit Care. 2024 Feb;79:154426. doi: 10.1016/j.jcrc.2023.154426. Epub 2023 Sep 25. PMID: 37757671.
  4. Hmidan Simsam M, Delorme L, Grimm D, Priestap F, Bohnert S, Descoteaux M, Hilsden R, Laverty C, Mickler J, Parry N, Rochwerg B, Sherman C, Smith S, Toole J, Vogt K, Wilson S, Ball I. Efficacy of high dose tranexamic acid (TXA) for hemorrhage: A systematic review and meta-analysis. Injury. 2023 Mar;54(3):857-870. doi: 10.1016/j.injury.2022.12.029. Epub 2023 Jan 8. PMID: 36746710.
  5. Priestap F, Veens J, Vogt K. Transfer status may not be associated with worse outcomes in elderly trauma patients. Injury. 2023 May;54(5):1314-1320. doi: 10.1016/j.injury.2023.01.047. Epub 2023 Jan 29. PMID: 36737269.
  6. Britton J, Jacobs K, Haidar T, Stolworthy C, Armstrong A, Merritt N, Parry N, Vogt K, Priestap F. Child restraint systems: Understanding confidence in proper use and addressing the need for education. Heliyon. 2023 Jul 10;9(7):e17409. doi: 10.1016/j.heliyon.2023.e17409. PMID: 37519765; PMCID: PMC10375554.
  7. Patton P, Vogt K, Priestap F, Parry N, Ball IM. Intravenous lidocaine for the management of traumatic rib fractures: A double-blind randomized controlled trial (INITIATE program of research). J Trauma Acute Care Surg. 2022 Oct 1;93(4):496-502. doi: 10.1097/TA.0000000000003562. Epub 2022 Feb 7. PMID: 35137728.
  8. Smith S, Allen L, Khwaja K, Joos E, Ball CG, Engels PT, Naji F, Lampron J, Widder S, Minor S, Jessula S, Parry NG, Vogt KN. Management of vascular trauma across Canada: A cohort study with implications for practice. Injury. 2022 May;53(5):1662-1666. doi: 10.1016/j.injury.2021.12.052. Epub 2022 Jan 2. PMID: 35012752.
  9. Vogt K, Kaminsky M, Joos E, Ball CG; Evidence Based Reviews in Surgery (EBRS) Group. Universal screening for blunt cerebrovascular injury: A critical appraisal. Evidence-based reviews in surgery. J Trauma Acute Care Surg. 2021 Dec 1;91(6):e142-e145. doi: 10.1097/TA.0000000000003403. PMID: 34538824.
  10. Parry NG. Stopping extremity hemorrhage: More than just a tourniquet. Surg Open Sci. 2021 Nov 17;7:42-45. doi: 10.1016/j.sopen.2021.11.003. PMID: 35028549; PMCID: PMC8741618.
  11. Ball IM, Priestap F, Parry N, Pace J, Vogt KN. Drug use in Canadian patients with trauma after cannabis legalization. Can J Surg. 2021 Jul 23;64(4):E403-E406. doi: 10.1503/cjs.000620. PMID: 34296708; PMCID: PMC8410467.
  12. Makish A, Priestap F, Vogt KN, Parry NG, Sibbald R, Ball I. Medical assistance in dying and the trauma patient. J Trauma Acute Care Surg. 2021 Jun 1;90(6):e155-e157. doi: 10.1097/TA.0000000000003130. PMID: 34016933.
  13. Curtis RM, Vogt K, Parry N, Priestap F, Leeper WR, Mujoomdar A, Kribs S, Ball IM. Retrievable inferior vena cava filter for primary prophylaxis of pulmonary embolism in at-risk trauma patients: A feasibility trial. Injury. 2021 May;52(5):1210-1214. doi: 10.1016/j.injury.2020.11.073. Epub 2021 Jan 8. PMID: 33431162.
  14. Smith S, McAlister V, Parry N, Power A, Vogt K. Vascular trauma: Does experience in the United States apply to a Canadian centre? Can J Surg. 2019 Dec 1;62(6):499-501. doi: 10.1503/cjs.002317. PMID: 31782648; PMCID: PMC6877390.
  15. Moffat B, Vogt KN, Inaba K, Demetriades D, Martin C, Malthaner R, Gray DK, Parry NG. Introduction of a mobile device based tertiary survey application reduces missed injuries: A multi-center prospective study. Injury. 2019 Nov;50(11):1938-1943. doi: 10.1016/j.injury.2019.08.020. Epub 2019 Aug 16. PMID: 31447214.
  16. Smith S, White J, Wanis KN, Beckett A, McAlister VC, Hilsden R. The effectiveness of junctional tourniquets: A systematic review and meta-analysis. J Trauma Acute Care Surg. 2019 Mar;86(3):532-539. doi: 10.1097/TA.0000000000002159. PMID: 30507857.
  17. Pace J, Parry N, Vogt K, Hilsden R, Leeper RR, Markova Z, Priestap F, Younan J, Ball I. A clinical prediction model for raised intracranial pressure in patients with traumatic brain injuries. J Trauma Acute Care Surg. 2018 Aug;85(2):380-386. doi: 10.1097/TA.0000000000001965. PMID: 29787544.

Military/Combat

  1. Smith SA, Hilsden R, Patton P, Vogt K, Beckett A, Ball IM. Management of Rib Fractures in the Combat Environment. J Spec Oper Med. 2024 Mar 13:FTLJ-MQXX. doi: 10.55460/FTLJ-MQXX. Epub ahead of print. PMID: 38457121.
  2. Smith S, Liu M, Ball I, Meunier B, Hilsden R. A Systematic Review of Prehospital Combat Airway Management. J Spec Oper Med. 2023 Mar 15;23(1):31-37. doi: 10.55460/S3MI-TFX5. PMID: 36753714.
  3. Smith SA, White J, McGuire T, Meunier B, Ball I, Hilsden R. Combat Vascular Access: A Scoping Review. J Spec Oper Med. 2023 Oct 5;23(3):32-38. doi: 10.55460/4WHG-X7ZZ. PMID: 37490425.

If you have any questions about Trauma Research, please reach out to Fran Priestap, Trauma Epidemiologist at fran.priestap@lhsc.on.ca